The approach described in the journal Science does not train the immune system. Instead it mimics the way immune cells communicate with each other.
It is given as a nasal spray and leaves white blood cells in our lungs – called macrophages – on “amber alert” and ready to jump into action no matter what infection tries to get in.
The effect lasted for around three months in animal experiments.
I’m no immunologist, but there has to be a reason why we evolved so our immune system doesn’t constantly stay on “amber alert”. There has got to be drawbacks.
So one of the reasons asbestos is so dangerous is that it gets in your lungs where macrophages detect it as being foreign and try to destroy it. The issue is that asbestos is way larger than these cells and it’s pretty resilient so they can’t break it apart and eat it. The cells "get frustrated " so they start releasing inflammatory substances trying to find a way to neutralize this foreign body. That prolonged inflammation is what eventually leads to mesothelioma and other cancers.
I’m not sure how they plan to avoid the inflammation caused by these cells being in constant fighting infection mode.
But the way evolution works is “whatever works that keeps the species alive”.
We haven’t evolved reading glasses, but they are helpful devices with very few downsides.
That said, there may well be unintended consequences and effects, sure.
I think of it this way. The immune system is like an army, ready to fight off foreign invaders. If you were a king, would you want a huge standing army at all times, or the ability to draft soldiers as needed? Having a huge standing army is not only a waste of resources if there isn’t anything to fight, but your soldiers might get bored and invent things to fight or just stir up trouble.
So my guess is you’d be prone to inflammation and develop food sensitivities, but it’s a total guess. If they were the case though, chronic inflammation is really bad long term.
Probably why there are auto-immune disorders, no? When the body randomly chooses to attack itself. Not a scientist so just speculating.
On one hand I can see the benefit of using such a booster right before flu season. On the other hand, yeah does it have a crash at the end? Does an overactive immune system damage healthy tissues? Does it create inflammation response that leads to depression, fatigue, other chronic issues? There is A LOT that can go wrong there.
I’d be really worried about autoimmune reactions. I swear there’s been a few Trek episodes where some kind of universal vaccine has unintended consequences.
I’m not sure I’d put any truck into fictional sci-fi where everything needs a good story, so any positive needs a negative…
…but I get it. And yeah, it’s a worry.
Same. Every major corona infection I suffered has set off my immune system for months, leading to debilitating nerve and joint pain. Even some vaccinations trigger this.
Can you please CW this post, for people like RFK this could be really triggering of their emotions.
There are like a hundred or more causes of the common cold, some viruses and some bacteria. It doesn’t seem possible they would get all of them into one jab, let alone the flus and other coughs to boot. The flu is famously mutative too, it’s constantly evading immunity with new variations that make old jabs obsolete.
Read the article. It’s not a traditional vaccine as we know it, but it puts the immune system on a higher alert level in general, meaning it will have faster and stronger responses to any pathogens.
I personally expect that there will be downsides to that, which the researchers do acknowledge. But it’s interesting research nonetheless.
Interesting I will. Some vaccines already do that, the TB and Polio both boost Innate immunity, and produce lower death rates from all ailments, as confirmed by multiple independent studies, according to articles published in spring of 2020 in the NYTimes.
The TB is just given to kids I think, and lessens severity if not preventing infections completely, and I think had the more pronounced innate immunity.
My guy, if you’re going to criticize, at least skim the article. It’s not even an injection.
It’s not a critique, it’s a fact, that there are over a hundred causes of the common cold. If you don’t want to learn that fact go ahead and piss off.
The point is that nothing you said had anything to do with the article, so if you don’t want to fucking read the article before you spout off, it is YOU who should piss off.
That being said, once you do read the article, perhaps I would love to learn what relevant facts you have. But until then, you’re the asshole barging into the coffee shop MAKE ME A COFFEE NOW I DON’T CARE ABOUT ANYONE ELSE. Yeah, well, there’s a fuckin’ line here, man. Terrible analogy, but the point is that it is you who started off rude by commenting without bothering to read.
I notice that you were told you should read the article WELL before you replied to that person, so you already knew you should have read the article before being rude to them. Wow.
A vaccine against all the common colds alone would cover 200 separate viruses and bacteria. By definition, protecting against the common cold of 200 different pathogens is applicable to that fact.
You really think you have something here too, mentioning a fact that is applicable to the subject or no, if you don’t want to discuss that fact, then don’t remark on it. You are repeatedly remarking that facts about the common cold aren’t applicable to a discussion about the common cold, don’t remark on it then.
Well, kiddo, here’s the thing. I’m already firmly aware of how current vaccines work, and that they target specific viruses and bacteria. So your attempt to bring facts into the conversation was useless for me. I already know them.
And I already know something you don’t: That has nothing to do with what’s presented in this article.
So let me bring the salient part of the article to your attention:
Their approach marks a “radical departure” from the way vaccines have been designed for more than 200 years, they say.
Experts in the field said the study was “really exciting” despite being at an early stage and could be a “major step forward”.
Current vaccines train the body to fight one single infection. A measles vaccine protects against only measles and a chickenpox vaccine protects against only chickenpox.
This is how immunisation has worked since Edward Jenner pioneered vaccines in the late 18th Century.
The approach described in the journal Science does not train the immune system. Instead it mimics the way immune cells communicate with each other.
It is given as a nasal spray and leaves white blood cells in our lungs – called macrophages – on “amber alert” and ready to jump into action no matter what infection tries to get in.
The effect lasted for around three months in animal experiments.
So in other words, IF THIS WORKS, it does not work in the same way that you bring up, meaning your “fact” is USELESS and OFF-TOPIC, and had you spent two minutes of your time BOTHERING to read the article, you would have prevented yourself from looking like a stupid mothingfucking dumbass.
But no. Congrats, you stupid motherfucking dumbass, you not only look stupid, but you were stupidly rude about it on TOP of that.
Wow.
What a spectacular failure.
When you read the article, do let us know if you deign to grace us with more facts. We might honestly find them interesting. But until you do, know that you are WRONG and RUDE and please shut the hell up.
How does that invalidate someone contributing facts about the common cold? Like great, it’s a contribution explaining this from the article, but a vaccine against the common cold, does warrant sharing facts about the common cold, irrespective of the article.
Maybe you already know it’s 200 plus bacteria or viruses, many don’t. There’s no reason to take that confrontational attitude for sharing facts that are applicable to the subject at hand. Any reasonable person would think so too.
The only thing worse than ignorance is arrogance. Thanks for the reminder.
Also, read the article. It’s pretty interesting science with some valid limitations and concerns.
You think that sounds smart don’t you? Yes, facts about the common cold can’t be mentioned on a vaccine claiming to protect against them all, so arrogant!
You’re a very bitter, spiteful person. Why do you feel the need to act like that?
